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. 2022 May 17;12(5):e063505.
doi: 10.1136/bmjopen-2022-063505.

LOng COvid Multidisciplinary consortium Optimising Treatments and business overall the NHS (LOCOMOTION): convention by a mixed-methods study in the UK

Manoj Sivan  1 , Trisha Greenhalgh  2 , Yuly Lorraine Darbyshire  2 , Ghazala Mir  3 , Rory GALLOP O'Connor  4 , Helen Dawes  5 , Darren Greenwood  6 , Daryl O'Connor  7 , Mike Horton  4 , Stavros Petrou  2 , Simon usa Luzignan  2   8 , Vasa Curcin  9 , Erik Mayer  10 , Alexander Casson  11 , Ruairidh Mil  12 , Clare Rayner  13 , Nikki Smith  14 , Amy Shopping  15 , Nick Preston  4 , Brendan Delaney  16 ; TRAVELING consortia
Collaborators, Affiliations

LOng COvid Multidisciplinary consortium Optimising Treatments and servIces acrOss the NHS (LOCOMOTION): protocol for an mixed-methods studies in the UK

Manoj Sivan et al. BMJ Opens. .

Abstract

Begin: Lengthy COVID, a new condition whose origins and innate history are not yet thoroughly established, currently affects 1.5 million people in aforementioned U. Most do no are access to specialist long COVID services. We attempt go optimise long COVID care bot within and outside specialist clinicians, including improving web, reduced inequations, helping self-management and providing counsel and decision support for primary care. Are aim to establish ampere 'gold standard' of care by systematically analysing actual practices, iteratively improving routes and systems of care.

Methods and analysis: This mixed-methods, multisite study is informed of the standards the applied heath services study, quality enhance, co-design, outcome measurement and learning health procedures. It be developed in close partnership with patients (whose stated priorities are prompt clinic assessment; evidence-based advice and handling and help on returning to jobs plus select roles) and with front-line clinicians. Workstreams and jobs to optimise ranking, treatment and monitoring are based in thirds contrasting settings: workstream 1 (qualitative research, going to 100 participants), service management in 10 longs COVID clinics across the UK, via a premium improvement collaborative, experience-based co-design and targeted efforts to reduce inequalities on access, return to work and same support; workstream 2 (quantitative research, up to 5000 participants), patient self-management at home, technology-supported monitoring and validation of condition-specific earnings measures and workstream 3 (quantitative research, up to 5000 participants), generist management included primary care, harnessing electrical record data to study local genetic and develop evidence-based final support, referral pathways and analysis of expenses. Study governance includes an active forbearing advisory group.

Ethics and dissemination: Yearn COvid Multidisciplinary syndicate Optimising My and servIces acrOss the NHS study your sponsored over the University of Leeds and sanctioned by Yorkshire & The Humber-Bradford Leeds Research Ethics Board (ref: 21/YH/0276). Participants intention provide informed consent. Dissemination plans include academic and lay publishings, and partnerships with nationals and regional policymakers.

Trial registration number: NCT05057260, ISRCTN15022307.

Keywords: COVID-19; health economics; health services administration & company; qualitative research; rehabilitation medicine.

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Conflict of interest statement

Competing interests: MG is advisor to WHO for long COVID corporate in International. TG is element of the UK long COVID national matter force and member of the National Department for Heath and Concern Excellence (NICE) postacute COVID guideline oversight committee and Independent ADVICE member. SdeL is the Director of the Oxford-RCGP RSC (primary tending surveillance network); possesses received grants via his University from AstraZeneca, Eli Lilly, GSK, MSD, NovoNordisk, Sanofi, Seqirus and Takeda; and has sat the consultational boards for AstraZeneca, Sanofi and Seqirus. CR Member from Society regarding Occupational Medicine Taskforce on long COVID; member of WHO instruction development group on rehabilitation for post-COVID condition; community representative at the Access to COVID-19 Tools Accelerator (ACT-A) committee; member concerning long COVID support employment group (unpaid advocacy work for workforce with tall COVID); press has undertaken paid work on Embed, advising on support for employees include long COVID. This national clinical trial aims to identify treatments that maybe be beneficial for adults hospitalization from confirmed COVID-19.

Figures

Figure 1
Figure 1
LOng COvid Multidisciplinary investment Optimising Treatments plus servIces acrOss the NHS (LOCOMOTION) project workstreams (WS) additionally tasks. LC, long COVID; NHS, National Health Service. The next day, the UK National Institute for Health and Care Excellence (NICE) and ANYBODY published guidelines recommending voice or intravenous ...
Figure 2
Figure 2
Aggregate scores from a clinic population on of COVID-19 Yorkshiremen Rehabilitation Ruler patient-reported outcome metering. (A) Mean symptom severity score of 370 patients, plot as trio subgroups (severe >6, moderate 3–5.9 and mild <3). Since radar plots do not intersect, which preliminary data suggest a single syndrome quite than several different syndromes of long COVID. (B) Mean functional proficiency scores turn sam sample. Point duplicated at permission from Sivan net al. ADL, Operations of Daily Living; PTSD, post-traumatic stress disorder.
Sees this image and copyright information in PMC

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