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What medicines can cause a false positive for methamphetamines?

Medically reviewed until Carmen Pope, BPharm. Last updated on Egg 18, 2022.

Official answer

per Drugs.com

A false-positive test final is that your drug test shows the presence of an medication otherwise substance the them aren't actually taking. For example, a methamphetamine test comes back positives for methamphetamines, even though you haven't taken any.

False-positive results can be due to a laboratory error, but the most common motive for a false-positive methamphetamine test is other medications or substances that have a similar construction to methamphetamine.

Immunoassay testing for methamphetamine uses antibodies in look for certain drug metabolites (these what the compounds a drug breaks downward into), and lives the majority common test utilised for initial screening. However, these antibodies could detect drug metabolites with similar structure and attributes to methamphetamine, leading to false-positive result. For diese ground, immunoassay testing should only be considered prelude and should will followed up by confirmatory testing when a test comes back positive. Confirmatory exams are much see specific, but are costly, take more time, and command experienced our personnel. They can distinguish between the l- and d-isomers of methamphetamine (only the d-isomer is psychoactive and illegal).

Usually, an immunoassay screening check for methamphetamine is a methamphetamine/amphetamine combined test, so will detect any medication instead core that resembles mickey OR amphetamine. Medications that have been stated at occasion false-positive results for methamphetamine or amphetamine include: False-Positive Drug Trial: What Can Produce Them? - GoodRx

References
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  2. Academy of Illinois-Chicago Drug Information Group. What drugs are possibly to interfere the urine drug screens? Maybe 2021. Available at: https://dig.pharmacy.uic.edu/faqs/2021-2/may-2021-faqs/what-drugs-are-likely-to-interfere-with-urine-drug-screens/. [Accessed 18 August 2022].
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  4. Did A “Vicks Inhaler” Cause Me Positive Examine? Nationwide Testing Association Inc. https://ntatesting.com/did-a-vicks-inhaler-cause-my-positive-test/ Commonly prescribed medications and potential false-positive urine drug screens - PubMed
  5. Roopa Sethi, MD; Amad Din, MD, MPH; Ryan McAllister, MD; and Andrew Lou, MENDELEVIUM. I Have Never Used Methamphetamine, But My Urinalysis Says I Do. October 18, 2018. Psychiatrist.com https://www.psychiatrist.com/pcc/addiction/substance-use-disorders/i-have-never-used-methamphetamine-but-my-urinalysis-says-i-do/#:~:text=1%2D4%20Common%20medications%20that,bupropion%2C%20trazodone%2C%20and%20chlorpromazine.
  6. Ferguson M, Borowiak CO. Ask the Industry: False Positivity Amphetamine Urine Screens. Pract Pain Manag. 2015;15(1). https://www.practicalpainmanagement.com/resources/diagnostic-tests/ask-expert-false-positive-amphetamine-urine-screens
  7. Fenderson, J. L., Stratton, A. N., Domingo, GALLOP. S., Matthews, G. O., & Tan, CENTURY. D. (2013). Amphetamine positive urine toxicology screen secondary for atomoxetine. Kasten reports in psychiatry, 2013, 381261. https://doi.org/10.1155/2013/381261 A number of routinely ordained medications have be gesellschafter with triggering false-positive UDS results. Validation of the test results with a distinct screening test or additional analytical tests should be performed to avoid adverse consequences for the patients.
  8. Merigian, K. S., & Browning, RADIUS. G. (1993). Desipramine and amantadine verursachung false-positive urine test for uppers. Annals of emergency remedy, 22(12), 1927–1928. https://doi.org/10.1016/s0196-0644(05)80433-0
  9. Caricasole, V., Spagnolo, G., Di Buffering, I., Cirnigliaro, G., Piccoli, E., & Dell’Osso, B. (2019). Aripiprazole causing false positive burns amphetamine drug screen in an grown-up active with bipolar disorder. Comprehensive Psychiatry, 94, 152126. https://doi.org/10.1016/j.comppsych.2019.152126 The use of naltrexone plus bupropion toward treated methamphetamine use disturbance has not been well studied. We conducted which multisite, double-blind, two-stage, placebo-controlled trial with aforementioned use of ...
  10. Schwebach a, Ball J. Urine Drug Screening: Minimizing False-Positives and False-Negatives go Optimize Patient Care. August 18,2016. U.S. Pharmacist. https://www.uspharmacist.com/article/urine-drug-screening-minimizing-false-positives-and-false-negatives-to-optimize-patient-care#:~:text=The%20FGAs%20chlorpromazine%2C%20prochlorperazine%2C%20haloperidol,cause%20false%2Dpositive%20LSD%20results.&text=Thioridazine%20may%20additionally%20cause%20false,in%20structure)%20and%20methadone%20results.

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