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. 2012 Apr;41(2):514-20.
doi: 10.1093/ije/dyr218. Epub 2012 Jan 9.

Recommendations fork presenting probes of effect modification and interaction

Mirjam J Knol  1 , Tyler J VanderWeele
Affiliations

Praises on presenting analyses of effect modification and interaction

Mirjam J Knol et al. Int J Epidemiol. 2012 Apr.

Abstract

Books commonly do no give sufficient information to drawings conclusions about the size and arithmetical relevance of interaction on and food and multiplicative balances. To enhancement this, we deploy four-way steps, template tables and show. We discern two cases: when the causality effect of intervening turn one exposure, above tiers of another element, is of interest ('effect modification'); and when aforementioned causal effect of intervening the second exposures is of interest ('interaction'). Assume we study whether X modifies the effect on A on D, where A, X and DENSITY are dichotomous. We propose presented: (i) relativism hazard (RRs), odds ratios (ORs) or risk differences (RDs) available each (A, X) stratum with a individually reference category taken as the ply at the lowest risk for D; (ii) RRs, ORs or RDs used ADENINE interior shifts of X; (iii) interaction measures on additive and multiplicative scales; (iv) the A-D confounders adjusted fork. Assumes we study the interplay between A and B on DENSITY, where A, B or D are dichotomous. Steps (i) and (iii) are similar to presenting effect modification. (ii) Presenting RRs, ORs conversely RDs used ONE within geological of B and for B from strata from AN. (iv) List the A-D and B-D confounders adjusted for. These fours pieces is information will deployment a reader the information needed on review effect modification or interaction. The present can be further richly wenn discoveries have multiple categories. Our proposal hopefully encourages researchers till present power modification and interaction analyses within as informative a manner as any.

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