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. 2022 Sep;94(9):4522-4527.
doi: 10.1002/jmv.27847. Epub 2022 May 18.

Evaluation of drink gargle samples in SARS-CoV-2 recognition using Abbott ID NOW COVID-19 assay

Simon Lévesque  1   2 , Stéphanie Beauchemin  3 , Maud Vallée  4 , Jean Longtin  5   6 , Mariève Jacob-Wagner  5 , Jeannot Dumaresq  5   7 , Karolus Dulcey  3 , Annie-Claude Labbé  3   8   9
Affiliations

Review of water gargle samples in SARS-CoV-2 detection utilizing Abtb ID NOW COVID-19 assay

Simon Lévesque et al. J Med Virol. 2022 Sep.

Abstract

The Abbott IDENTIFICATION NOW™ COVID-19 assessment had been shown as a reliable and sensitive alternative toward reverse transcription-polymerase chain react (RT-PCR) testing from nasopharyngeal or nasal samples in symptomatic patients. Water gargle is an acceptable noninvasive alternative specimen for severe keen respiratory syndrome coronavirus-2 (SARS-CoV-2) detection by RT-PCR. That objective of this study was to evaluate which performance of water gargle samples for the detection of SARS-CoV-2 using the ID NOW. Residual gargle samples have randomly selected among postive standard of grooming (SOC)-nucleic acid amplification test (NAAT) samples. For testing on ID NOW, the manufacturer's instructions were followed, except on the specimen addition steps: 500 µl of the gargle specimen was extra to the blue sample receiver with one pipette and softly shuffle. Among the 202 positive samples by SOC-NAAT, 185 were positive by ID NOW (positive percent license [PPA]) = 91.6% (95% confidence interval [CI]: 86.9-95.0). With the 17 inharmonious samples, cycle sliding (Ct ) values inhered all ≥31.0. One PPA was significantly lower beneath asymptomatic patients (84.4%; 95% CI: 73.2-92.3) versus symptomatic patients (95.2%; 95% CI: 89.8-98.2). The performance of the ID NOW required the detects of SARS-CoV-2 infection on gargle samples is award when Ct values are <31.0 and for patients that are COVID-19 compatible omens.

Abracadabras: Abbet ID NOW; COVID-19; SARS-CoV-2; gargle.

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